Beiträge zur Pneumatologie des Blutes. Offprint. Insc. by Carl Ludwig

1859. Sechenov, Ivan Mikhailovich (1829-1905). Beiträge zur Pneumatologie des Blutes. Offprint from Sitzungsberichte der mathem.-naturw. Classe der kaiserlichen Akademie der Wissenschaft 36 (1859). 29pp. Plate. 237 x 151 mm. Modern marbled boards, original printed front wrapper bound in. Very good. Presentation Inscription from Carl Ludwig (1816-95), one of the founders of modern physiology, to “Prof. Bischoff” (possibly Theodor Ludwig Wilhelm von Bischoff [1807-82]): “Herrn Prof Bischoff mit v. herzl. Gruss v. C. Ludwig.” First Edition, Offprint Issue of Sechenov’s first important medical paper, inscribed by Sechenov’s teacher Carl Ludwig, who may have been a co-author.. Sechenov, the founder of Russian physiology, was a student under Carl Ludwig when he published the present work describing investigations of blood gases he and Ludwig had performed in 1858 following the publication of Meyer’s Die Gase des Blutes (1857). “In 1858 Carl Ludwig and his then student, Ivan Sechenov, constructed a pump based on a Torricellian vacuum (a vacuum above a column of mercury in a barometer) to liberate the gases from the blood. This pump was one of the first to give accurate, reliable measurements that later proved to be largely correct. The manually operated ‘blood-gas pump’ required considerable exertion to operate, with up to 20 extraction cycles performed to complete the process” (Ball and Featherstone, p. 419). The pump is illustrated in the plate. P. Astrup and J. W. Severinghaus, “Blood gas transport and analysis,” in J. B. West, ed., Respiratory Physiology: People and Ideas, pp. 75-107. C. M. Ball and P. J. Featherstone, “Blood gas analysis: From laboratory to bedside,” Anaesthesia and Intensive Care 49 (2021): 419-421. The recipient of this presentation copy may have been Theodor Ludwig Wilhelm von Bischoff, a German biologist and physician who made important contributions to embryology. . (Inventory #: 51945)